New breast cancer surgery could spare women unnecessary lymph node removal
NCT ID NCT07278726
First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 22 times
Summary
This study aims to see if a less invasive surgery, called targeted axillary dissection (TAD), can safely replace full axillary lymph node dissection (ALND) in women with early-stage luminal breast cancer that has spread to only 1 or 2 lymph nodes. Participants will have a marker placed in the suspicious lymph node, which is then removed along with sentinel nodes. Full ALND is only done if 3 or more nodes are positive, reducing unnecessary surgery and side effects. The study enrolls 150 women aged 18-90 who do not need chemotherapy before surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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AO San Giovanni Addolorata
NOT_YET_RECRUITINGRoma, Italy, 00184, Italy
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ASST Sette Laghi - Ospedale di Circolo e Fondazione Macchi
NOT_YET_RECRUITINGVarese, Italy, 21100, Italy
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AUSL Romagna - Presidio Ospedaliero Morgagni-Pierantoni
NOT_YET_RECRUITINGForlì, Italy, 47121, Italy
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Azienda Ospedaliera Universitaria Federico II
NOT_YET_RECRUITINGNaples, Italy, 80131, Italy
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Azienda Ospedaliera Universitaria Pisana
NOT_YET_RECRUITINGPisa, Italy, 56100, Italy
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Azienda sanitaria universitaria Giuliano Isontina
NOT_YET_RECRUITINGTrieste, Italy, 34148, Italy
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Ente Ospedaliero Cantonale
NOT_YET_RECRUITINGLugano, Switzerland, CH-6500, Switzerland
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European Institute of Oncology
RECRUITINGMilan, Italy, 20141, Italy
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Fondazione IRCCS Istituto Nazionale Tumori di Milano
NOT_YET_RECRUITINGMilan, Italy, 20133, Italy
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
NOT_YET_RECRUITINGRoma, Italy, 00136, Italy
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IRCCS AOU di Bologna - Policlinico di Sant'Orsola
NOT_YET_RECRUITINGBologna, Italy, 40138, Italy
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IRCCS Humanitas Research Hospital
RECRUITINGRozzano, Italy, 20089, Italy
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Policlinico San Matteo
NOT_YET_RECRUITINGPavia, Italy, 27100, Italy
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Presidio Ospedaliero "G. Bernabeo"
NOT_YET_RECRUITINGOrtona, Italy, 66026, Italy
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Conditions
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