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New study tests safer ways to treat bladder leaks in older women prone to falls

NCT ID NCT05880862

First seen Nov 21, 2025 · Last updated Jun 23, 2026 · Updated 27 times

Summary

This study compared pelvic floor muscle training with two medications (mirabegron and trospium) for treating urgency urinary incontinence in women aged 60 and older who are at high risk of falling. Forty-eight women were randomly assigned to one of three groups and followed for six months. The goal was to see if a larger trial is possible and how each treatment affects bladder symptoms and fall risk.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Texas Medical Branch at Galveston

    Galveston, Texas, 77555, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pelvic floor muscle training, mirabegron, or trospium chloride

What this could lead to

If successful, this could point toward a safer, more effective treatment for urgency incontinence in older women who are at risk of falling.

What could go wrong

This is a very early feasibility study with only 48 participants, so results may not apply broadly. The drugs can cause side effects like dizziness or dry mouth, which could increase fall risk.

Conditions

The condition(s) this trial relates to.

overactive bladder Urinary Incontinence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.