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Weight loss and drug combo may dissolve kidney stone risk

NCT ID NCT04370093

First seen Sep 30, 2025 · Last updated Jun 18, 2026 · Updated 31 times

Summary

This study looked at whether the drug pioglitazone, weight loss, or both could help prevent uric acid kidney stones in overweight people. 29 adults with a history of these stones were randomly assigned to one of three groups for 24 weeks. The main goal was to see if these treatments could raise urine pH, which makes stones less likely to form.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390-9107, United States

Conditions

The condition(s) this trial relates to.

acute urate nephropathy nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.