Scientists probe muscle secrets behind stubborn shoulder pain
NCT ID NCT06472349
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how the upper trapezius muscle works and its structure in people with chronic shoulder pain compared to healthy individuals. Researchers will measure muscle activation, thickness, fat content, and shoulder movement using ultrasound, MRI, and other tools. The goal is to better understand what causes ongoing shoulder pain, which could lead to improved treatments down the road.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help identify key factors that contribute to chronic shoulder pain, potentially guiding more targeted treatments in the future.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly test any therapy, and results may not lead to immediate clinical changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2023
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Community Sample
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Chronic shoulder pain group * 18-50 years old18-50 years old * unilateral and non-traumatic shoulder pain * pain duration longer than 3 months * pain intensity more than VAS=2 during movement * presence 3 of 5 positive pain provocation tests: Hawkins-Kennedy test, Jobe test, or Neer's test Painful Arc, and Resistance Test against External Rotation. * Healthy control group * presenting no shoulder pain at rest or during daily activities * negative results of the pain provocation test: Hawkins-Kennedy test, Jobe test, Neer's test, Painful Arc, Resistance Test against External Rotation and Spurling's neck compression test. Exclusion Criteria: \- Chronic shoulder pain group * history of significant shoulder trauma, such as fracture or ultrasonography clinically suspected full thickness cuff tear * recent shoulder dislocation in the last 2 years * diagnosis of adhesive capsulitis characterized by a gradual and painful loss of both active and passive ROM in all shoulder planes, primarily external rotation * shoulder pain originating from the cervical spine by using Spurling's neck compression test * shoulder pain owing to the following disorders: arthritis (e.g., rheumatoid arthritis, osteoarthritis of shoulder complex), neurologic (e.g., stroke), neoplastic (e.g., breast cancer). and/or referred pain (e.g., visceral referred pain) * corticoid injections over the shoulder during 6 months prior to the study * history of shoulder and neck surgery
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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National Yang Ming Chiao Tung University
RECRUITINGTaipei, 11221, Taiwan
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