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New drug trial aims to ease joint and spine pain in psoriatic arthritis

NCT ID NCT06454188

First seen Apr 05, 2026 · Last updated May 22, 2026 · Updated 4 times

Summary

This study tests whether upadacitinib, a daily pill, can reduce inflammation and improve symptoms in people with active psoriatic arthritis that also affects the spine. About 100 adults who have not responded well to standard treatments will receive either upadacitinib or a placebo for 12 weeks. The main goal is to see changes on MRI scans and in disease activity scores.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Groupe de Recherche en Maladies Osseuses (G.R.M.O.) Inc.

    RECRUITING

    Québec, Quebec, G1V 3M7, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health and Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Ottawa Hospital Research Institute

    RECRUITING

    Ottawa, Ontario, K1H 7W9, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospitals Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.