Can digital therapy break the cycle of worry and rumination?
NCT ID NCT07577401
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will enroll 500 adults with high levels of repetitive negative thinking (like worry or rumination) to understand why cognitive-behavioral therapy helps. Participants will receive one of two digital therapy programs: one focusing on concrete thinking, the other on self-compassion. The goal is to identify which skills are most important for reducing repetitive negative thoughts and improving mental health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Digital therapy lessons and coaching (Be Specific and Be Kind behavioral interventions)
- What this could lead to
- If successful, this could reveal which parts of cognitive-behavioral therapy are most effective for reducing repetitive negative thinking, helping to improve future treatments.
- What could go wrong
- This is an early-stage study focused on understanding mechanisms, not testing a new treatment. Results may not lead to immediate clinical changes, and the digital format may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18+ years * Able to provide a valid Imperial Valley College email address * Access to a suitable smartphone/device (iPhone 8+ running iOS 16.4 or higher, or Android version 8 or higher) * Access to internet * Elevated repetitive negative thought (RNT) based on scores from Ruminative Response Scale Brood subscale (RSS-brood) and Penn State Worry Questionnaire (PSWQ) Exclusion Criteria: * Concurrent psychotherapy * Self-reported current or past diagnosis or treatment for Psychosis * Self-reported current or past diagnosis or treatment for Bipolar disorder * Self-reported current or past diagnosis or currently receiving, or waiting to receive, treatment for substance abuse/dependence * Self-reported current diagnosis or currently receiving, or waiting to receive, treatment for alcohol abuse/dependence * Antidepressant/anxiolytic medication that has changed in dose or nature in last 6 weeks * Current severe PTSD defined as measured by the adapted International Trauma Questionnaire * Active suicidal thoughts or self-harm
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Imperial Valley College
Imperial, California, 92251, United States
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