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Could your heart and nerves explain Post-Stroke exhaustion?

NCT ID NCT06292377

Knowledge-focused Sponsor: Brugmann University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is looking for 250 stroke survivors to understand why many feel overwhelming tiredness after a stroke, known as post-stroke fatigue. Researchers will measure heart rate variability, heart function, and blood markers to see if problems with the autonomic nervous system or heart contribute to this fatigue. Participants will be followed for several months to track their fatigue levels and overall recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could reveal why some stroke survivors suffer from long-term fatigue, pointing toward future treatments or prevention strategies.
What could go wrong
This is an observational study, not a treatment trial. It may find no clear link between heart/nerve function and fatigue, or the results may not apply to all stroke patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2024

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 * First-ever (suspicion of) ischemic stroke based on clinical examination and/or brain imaging * Onset \< 72h at time of inclusion * Admitted at the stroke unit of CHU Brugmann and UZ Brussel * Ability to participate in assessment of fatigue, cognitive, mood and sleep disturbances * Ability to undergo MRI of the brain Exclusion Criteria: * Unable to speak French or Dutch * Pre-existing stroke or other structural brain lesion * Life expectancy \< 1 year * Severe language impairment or dementia impeding assessment of fatigue, cognitive, mood and sleep disturbances * Pregnancy or wish to become pregnant

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Conditions

The condition(s) this trial relates to.

ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHU Brugmann

    RECRUITING

    Brussels, 1020, Belgium

  • UZ Brussel

    RECRUITING

    Brussels, 1090, Belgium

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