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Study aims to define what 'Meaningful' pain relief really means for surgery patients

NCT ID NCT04811209

Knowledge-focused Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is trying to figure out what counts as a meaningful improvement in pain after major orthopedic surgeries like hip, knee, shoulder, or spine procedures. Researchers will ask 300 adults to rate their pain and recovery before and after surgery. The goal is to set clear benchmarks that doctors can use to know if a patient's pain treatment is working well enough.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better understand what level of pain relief patients consider worthwhile after surgery, leading to more personalized pain management.
What could go wrong
This is an observational study, not testing a new treatment. It may not change practice directly, and results might not apply to all types of surgery or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 300 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2021

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Study patients will be recruited at Toronto Western Hospital

Ages

18 to 80 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18-80 years * ASA class I - III * Primary elective surgery * unilateral major shoulder surgery e.g., stabilization and arthroplasty procedures: * unilateral total hip replacement * unilateral total knee replacement, and * spinal decompression + fusion involving ≥ 2 levels. * Hospital admission for ≥ 24 hours after the surgery Exclusion Criteria: * Inability to give informed consent * Poor English comprehension * Psychiatric disorders e.g., dementia * Known allergies to morphine / hydromorphone * Chronic substance abuse and use of recreational drugs * Any medical disorder that impairs accurate and objective completion of questionnaires

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pain management

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Toronto Western Hopspital

    RECRUITING

    Toronto, Ontario, M5T2S8, Canada

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