New study aims to uncover causes of Anesthesia-Related low blood pressure
NCT ID NCT05954832
First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 2 times
Summary
This study is observing 250 adults undergoing surgery to understand how heart function and blood flow change when general anesthesia is given. Researchers focus on those who develop low blood pressure after anesthesia induction. Using echocardiography and blood pressure measurements, they hope to identify key factors that lead to this common complication.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors predict and prevent dangerous drops in blood pressure during surgery, improving patient safety.
- What could go wrong
- This is an observational study, not testing a treatment. It may not lead to immediate changes in practice, and results might not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 250 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2023
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients requiring general anesthesia for surgery
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients ≥ 18 years of age requiring general anesthesia for surgery * Intubation required for anesthetic management / surgery * Anticipated prep time before incision of 20 minutes * Baseline MAP \>70mmHg Exclusion Criteria: * History of coronary artery disease * History of cardiac disease (e.g., HTN, arrythmias, valvular and structural abnormalities) * History of peripheral artery occlusive disease * Beta-blocker use * Anti-hypertensive medication use * Patients with epidural, spinal, paravertebral, serratus blocks preoperatively * Patients requiring rapid sequence induction (where intubation occurs concurrently with induction) * Emergency surgery
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Memorial Sloan Kettering Cancer Center (All protocol activites)
RECRUITINGNew York, New York, 10065, United States
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Other studies related to the condition(s) this trial covers.
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- Which epidural technique best handles a cesarean emergency?