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Why do some feel more breathless? new study aims to find out

NCT ID NCT07472738

Knowledge-focused Sponsor: Beijing Chao Yang Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study is investigating how patients with chronic airway diseases like COPD and asthma perceive breathing difficulty. Researchers will assess about 950 participants (800 patients and 150 healthy volunteers) using questionnaires, lung function tests, blood samples, and brain scans. The goal is to group patients based on their perception of breathlessness and other traits, which could lead to more personalized care in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better understand why some patients feel more breathless than others, leading to more personalized treatment plans for chronic airway diseases.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly improve health. The findings may not lead to immediate changes in care, and results depend on how well participants report their symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 950 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of two groups: 1) a patient cohort of approximately 800 individuals with chronic airway diseases (Chronic Obstructive Pulmonary Disease or Asthma) recruited from hospital clinics and community screening; and 2) a control cohort of approximately 150 healthy volunteers. All participants will be aged between 20 and 75 years.

Ages

20 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion Criteria for Chronic Airway Disease Patients: 1. Age 20-75 years. 2. Meets the diagnostic criteria for COPD according to the 2022 GOLD guidelines OR meets the diagnostic criteria for asthma according to the 2022 GINA guidelines. 3. Willing and able to provide informed consent. * Inclusion Criteria for Healthy Controls: 1. Age ≥20 years. 2. No history of asthma symptoms or diagnosis of chronic respiratory diseases such as asthma or COPD. 3. Willing and able to provide informed consent and comply with the study protocol. Exclusion Criteria: * (applies to all participants): 1. Respiratory tract infection, COPD acute exacerbation, or asthma acute exacerbation within the past 3 months. 2. Presence of other diseases causing significant lung tissue destruction, such as severe bronchiectasis or tuberculosis. 3. History of thoracic or abdominal surgery within the past 3 months. 4. Heart rate \>120 beats per minute. 5. Ongoing anti-tuberculosis treatment. 6. Presence of other severe, uncontrolled systemic diseases. 7. Pregnant or lactating women.

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Conditions

The condition(s) this trial relates to.

asthma chronic obstructive pulmonary disease disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Asthma (diagnosis) Chronic airway diseases Chronic obstructive pulmonary disease (COPD)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Beijing Chao-Yang Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.