Ultrasound may predict breathing readiness without tube blocking
NCT ID NCT07564258
First seen Jun 27, 2026 · Last updated Aug 26, 2026 · Updated 4 times
Summary
This study will test whether ultrasound measurements of the diaphragm can estimate a standard breathing effort test (P0.1) in 40 intubated patients. During a spontaneous breathing trial, researchers will compare diaphragm movement and thickness with the P0.1 reading. If the ultrasound matches well, it could offer a non-invasive way to assess breathing drive in patients who cannot have the standard test.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- diaphragm ultrasound
- What this could lead to
- If successful, this could lead to a simpler, non-invasive way to measure breathing effort in patients on breathing machines, helping doctors decide when to remove the tube.
- What could go wrong
- This is a small, early-stage study (40 participants) that only tests a correlation, not a treatment. The ultrasound method may not be accurate enough to replace the standard test in all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients admitted to the intensive care unit who are intubated or have undergone a tracheostomy.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * \- Age ≥ 18 years old * Patient intubated or tracheostomized * Decision by the clinician in charge to initiate a SBT * After information, the patient or next of kind did not refuse to participate (according to the French law, written informed consent is waived) Exclusion Criteria: * \- Suspicion of diaphragmatic nerves injury * Preexisting neuromuscular disease * Spinal cord injury above C5 * Neuromuscular blockade within last 24 hours * Body mass index \> 40 kg/m2 * Pregnancy or breast feeding * Patient under legal protection
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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