Bladder ultrasound may predict BPH drug success
NCT ID NCT07306767
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 130 men aged 50+ with enlarged prostate (BPH) causing urinary symptoms. Researchers used an ultrasound to measure how far the prostate bulges into the bladder, then tracked symptom changes over 6 months of standard medication. The goal was to see if this simple measurement could predict who will respond well to drugs and who might need stronger treatment or surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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130 people
The number who actually took part.
- Started
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Dec 2024
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Men aged 50 years or older with moderate to severe lower urinary tract symptoms secondary to benign prostatic hyperplasia attending urology outpatient services at Ain Shams University Hospitals.
- Ages
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50 years and older
- Sex
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Male participants only
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male participants aged 50 years or older. * Lower urinary tract symptoms secondary to benign prostatic hyperplasia. * Moderate to severe symptoms with International Prostate Symptom Score 15 to 35. * Prostate volume 30 to 100 millilitres. * Maximum urinary flow rate less than 15 millilitres per second. * No hydronephrosis due to bladder outlet obstruction. * Normal prostate-specific antigen or normal free-to-total prostate-specific antigen ratio. Exclusion Criteria: * History of prostate, bladder, or lower urinary tract surgery. * Neurological disease affecting lower urinary tract function. * Active urinary tract infection and/or symptomatic urinary tract stones. * Post-void residual urine volume greater than 200 millilitres. * Urethral stricture. * Prostate cancer or bladder cancer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ain Shams University Hospitals
Cairo, Cairo Governorate, 11511, Egypt
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Other studies related to the condition(s) this trial covers.
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