New combo therapy eases stiff calves in knee arthritis patients
NCT ID NCT07256054
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding high-power pain threshold ultrasound and vibration massage to standard treatment could help with calf muscle tightness in people with knee osteoarthritis. Sixty patients with moderate knee OA were split into three groups: standard care alone, standard care plus vibration, or standard care plus both vibration and ultrasound. The researchers measured calf flexibility, pain, and knee function before and after 12 sessions over four weeks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- high-power pain threshold ultrasound and vibration massage
- What this could lead to
- If it works, this could offer a simple, non-drug way to ease calf tightness and improve knee function in people with knee osteoarthritis.
- What could go wrong
- This is a small, completed trial with only 60 participants, so results may not apply to everyone. The outcomes are short-term and the treatment is an add-on, not a cure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Jun 2024
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age from 40 to 60 years' patients of chronic knee OA 2. Patient with unilateral knee OA grade II-III Kellgren and Lawrence (K/L) 3. Patients with BMI \< 30 kg/m² (not being classified as obese). 4. Patients who are able to walk with painful knee OAwithoutassistive devices. 5. Patients with knee pain intensity level at least \>3 cm on a 10 cm. VAS scale in activities such as going up-and downstairs, sitting and squatting. Exclusion Criteria: * Radiated pain from low back pain. * No radiographic evidence of knee OA or with mild OA (grade I according to K/L classification) or with severe OA (grade IV according to K/L classification). * Bilateral knee OA. * Loss of joint play in tibiofemoral and patellofemoral articulations. * Lower extremity fracture and surgery or trauma to the knee joint. * Neurological deficit or movement disorder related to lower limb. * Athletes or who had been treated with physiotherapy or medications during the previous 6 weeks. * Those who could not apply vibration and percussion stimuli. * Those who had varicose veins.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Physical Therapy faculty, Cairo University
Cairo, Egypt
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