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Sugar water injection eases carpal tunnel pain in small study

NCT ID NCT07371221

Symptom relief Sponsor: Dr. Nafiz Korez Sincan State Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a single injection of 5% dextrose (sugar water) guided by ultrasound to separate the median nerve from surrounding tissues in 37 people with mild-to-moderate carpal tunnel syndrome. Participants were followed for 3 months to see if pain and hand function improved. The goal was to see if this simple procedure could be a safe and effective alternative to surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
5% dextrose solution
What this could lead to
If it works, this could offer a simple, non-surgical option to reduce pain and improve hand function in people with carpal tunnel syndrome.
What could go wrong
This is a small, single-group study with no comparison group, so results may not be generalizable. The procedure is still experimental and long-term benefits are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

37 people

The number who actually took part.

Started

Jun 2024

Finished

Jun 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 65 years * Electrophysiologically confirmed mild to moderate CTS on electroneuromyography (ENMG) * Paresthesia or dysesthesia that worsens at night or with repetitive wrist movement * Presence of at least one of the following clinical findings: 1. Numbness in the median nerve distribution 2. Decreased hand strength or thenar muscle weakness 3. Positive Phalen's test and/or Tinel's sign * Pain intensity of ≥3 on the Visual Analog Scale (VAS) Exclusion Criteria: * Previous carpal tunnel surgery * Severe CTS on ENMG * Polyneuropathy * Pregnancy * Injections in the same area within the last 3 months * Peripheral nerve injury, thoracic outlet syndrome, cervical radiculopathy, brachial plexopathy * Traumatic hand injury in the last 2 years * Inflammatory rheumatological disease * Thyroid and autoimmune disease

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carpal tunnel syndrome (CTS)

Contacts and locations

Locations

  • Dr. Nafiz Korez Sincan State Hospital

    Ankara, Ankara, 06340, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.