Quick ultrasound may spot High-Risk PE patients in the ER
NCT ID NCT05050617
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a simple bedside heart ultrasound can help predict which emergency patients with a pulmonary embolism (a blood clot in the lung) are likely to have serious complications within the next few days. Researchers will perform the ultrasound on 250 patients at the time of diagnosis and track their outcomes for up to 14 days. The goal is to see if signs of right heart strain on the ultrasound can identify high-risk patients better than current methods.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- point-of-care echocardiography (bedside heart ultrasound)
- What this could lead to
- If successful, this could give doctors a quick, reliable way to identify which pulmonary embolism patients are at highest risk of complications, helping them make faster treatment decisions.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly improve outcomes. The ultrasound findings may not prove accurate enough to change clinical practice, and the results may not apply to all hospitals or patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 250 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2021
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of ED patients over the age of 18 who have an acute pulmonary embolism identified on CT imaging.
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \>= 18 years of age * ED diagnosis of acute pulmonary embolism with identification on CT imaging Exclusion Criteria: * Age \<18 years of age * Inability to provide informed consent * Incarceration * Current PE previously diagnosed prior to index ED visit
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Wellspan York Hospital
RECRUITINGYork, Pennsylvania, 17403, United States
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