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Simple ultrasound may spot hidden leg swelling cause

NCT ID NCT06180122

Diagnosis Sponsor: Imperial College London Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study explores whether a vascular ultrasound can help diagnose May-Thurner syndrome, a condition where a vein in the pelvis is compressed, causing left leg swelling. Researchers will measure the vein's diameter in 40 adults with unexplained swelling and compare results to healthy individuals. The goal is to see if ultrasound is a reliable, non-invasive diagnostic tool.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Duplex ultrasound
What this could lead to
If successful, this could provide a non-invasive way to diagnose May-Thurner syndrome, reducing the need for more invasive tests.
What could go wrong
This is a small pilot study with only 40 participants, so results may not apply to everyone. The technique may not be accurate enough to replace current diagnostic methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Mar 2024

Finished

May 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant has the capacity to consent * Participant is required to have a vascular ultrasound scan in the vascular ultrasound department * Participant is 18 years of age or older at the start of the study. Exclusion Criteria: * Previous iliac vein intervention or treatment for iliac vein disease * Previous diagnosis of iliac vein thrombus * Pregnancy * Unable to provide appropriate informed consent * The participant does not require a vascular ultrasound as part of their routine care * Under 18 years of age at the start of the study

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Conditions

The condition(s) this trial relates to.

May-Thurner syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

May-thurner syndrome

Contacts and locations

Locations

  • Imperial College Healthcare NHS Trust

    London, Greater London, W6 8RF, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.