Simple ultrasound may spot hidden leg swelling cause

NCT ID NCT06180122

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study explores whether a vascular ultrasound can help diagnose May-Thurner syndrome, a condition where a vein in the pelvis is compressed, causing left leg swelling. Researchers will measure the vein's diameter in 40 adults with unexplained swelling and compare results to healthy individuals. The goal is to see if ultrasound is a reliable, non-invasive diagnostic tool.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Duplex ultrasound
What this could lead to
If successful, this could provide a non-invasive way to diagnose May-Thurner syndrome, reducing the need for more invasive tests.
What could go wrong
This is a small pilot study with only 40 participants, so results may not apply to everyone. The technique may not be accurate enough to replace current diagnostic methods.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Imperial College Healthcare NHS Trust

    London, Greater London, W6 8RF, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.