Ultra-Processed foods under the microscope: new study targets hidden health effects
NCT ID NCT07634159
First seen Jun 27, 2026 · Last updated Aug 25, 2026 · Updated 2 times
Summary
This study aims to find out if eating a lot of ultra-processed foods (like packaged snacks and sugary drinks) directly harms appetite and heart health, even without weight gain. Researchers will compare a high-UPF diet to a low-UPF diet in 40 healthy adults aged 20-60. Participants will eat both diets in a random order, and scientists will measure hormones, blood fats, and body changes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 20-60 years * Weight stable (less than 5% weight change in the past 3 months) * No plans to change weight * Willing to eat the study diet and a mixed diet * Habitually eats breakfast, lunch and dinner * Has provided informed consent to participate in the study Exclusion Criteria: * Allergy or intolerance to foods included in the study. Participants with lactose intolerance treated with lactase may participate if they take enzymes. * BMI \<18.5 or \>35 kg/m² * \>8h/week of intense physical activity * Use of medications known to significantly affect appetite (e.g., oral corticosteroids, antipsychotic medications, or GLP-1 receptor agonists) * Use of lipid-lowering medications (e.g., statins or PCSK9 inhibitors) * Diagnosed diabetes or capillary blood glucose at or above 12.2 mmol/L * Disease associated with malabsorption (e.g., inflammatory bowel disease or celiac disease) * Previous bariatric surgery * Established cardiovascular disease (heart failure, myocardial infarction, or stroke) or cancer * Pregnancy or breastfeeding, or plans to become pregnant or breastfeed during the study * Deemed likely to have poor adherence
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Gothenburg
RECRUITINGGothenburg, 40530, Sweden
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