Tiny dye dose may protect kidneys during leg-saving procedure
NCT ID NCT06835127
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether using a very small amount of contrast dye (less than 15 ml) is safe and works for opening blocked leg arteries in 18 patients with both severe leg ischemia and kidney impairment. The goal was to save the leg while protecting the kidneys. Results focused on kidney function, technical success, and avoiding amputation or dialysis.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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18 people
The number who actually took part.
- Started
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Sep 2024
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients suffering from renal impairment stage 2 to 4 and chronic -limb-threatening ischemia (CLTI)
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * CLTI * Prescheduled infrainguinal revascularization procedure * Renal disease stage 2-4 (eGFR \<60ml/minute/1.73m2) * Adequate pre- and post-procedural hydration protocol Exclusion Criteria: * Inadequate pre- and post-procedural hydration protocol * End-stage renal disease/ dialysis * eGFR \>60ml/minute/1.73m2) * Endovascular treatment of Iliac artery steno-oclussive disease * Allergy to contrast media
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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"ATTIKON" University General Hospital, , 1st Rimini St,
Chaïdári, Attica, 12461, Greece
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