New radiation combo may let rectal cancer patients skip surgery

NCT ID NCT04677413

Recruiting now Disease control Sponsor: University of Texas Southwestern Medical Center Source: ClinicalTrials.gov ↗

First seen May 02, 2026 · Last updated May 23, 2026 · Updated 6 times

Summary

This early-phase trial tests a new way to give radiation therapy for locally advanced rectal cancer. Instead of standard long-course radiation, patients receive several high-dose radiation sessions mixed with chemotherapy over a longer period. The goal is to see if this approach can shrink the tumor enough to avoid surgery. The study includes 27 adults with stage T3-4 or node-positive rectal cancer who have not had prior treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

UT Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390-8849, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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RECTAL CANCER