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Family ties: could Parents' personalities hold clues to mood disorder risks?
NCT ID NCT07679204
First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study looks at whether parents of people with bipolar II disorder or major depressive disorder have certain personality traits (called Type D, which involves negative emotions and social inhibition) and lower life satisfaction. Researchers compare these parents to parents of healthy individuals, as well as to patients themselves. The goal is to better understand family patterns that might help design future support programs.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could identify psychological traits in family members that may guide supportive interventions for relatives of people with mood disorders.
- What could go wrong
- This is an observational, cross-sectional study with a small sample size (180 participants), so findings may not apply broadly and cannot prove cause and effect.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2024
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consisted of adult participants aged above 18 years. The bipolar disorder type II (BD-II) group included consecutive patients diagnosed with BD-II and the major depressive disorder (MDD) group included consecutive patients diagnosed with MDD according to DSM-5-TR criteria who were admitted to the psychiatry outpatient clinic of Elazığ Fethi Sekin City Hospital (Turkey). The healthy control (HC) group consisted of individuals from the general population who applied to the hospital medical board and had no current or past psychiatric or significant medical disorders. Psychiatrically healthy mothers and/or fathers of members of the BD-II, MDD, and HC groups were also included in the study. All participants provided informed consent prior to enrollment.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
1. For Bipolar Disorder Type II (BD-II) Group: \*Inclusion Criteria: * Diagnosis of BD-II according to DSM-5-TR * Remission period * Age ≥ 18 years * Provided informed consent For Bipolar Disorder Type II (BD-II) Group: \*Exclusion Criteria: * Hypertension * Diabetes mellitus * Chronic kidney disease * Rheumatoid arthritis * Systemic lupus erythematosus * Cardiac illness * Severe neurological disorders * Immunological or systemic illness * Primary psychiatric disorders other than BD-II and not in remission for BD-II * Alcohol/drug/substance use 2. For Major Depressive Disorder (MDD) Group: \*Inclusion Criteria: * Diagnosis of MDD according to DSM-5-TR * Remission period * Age ≥ 18 years * Provided informed consent For Major Depressive Disorder (MDD) Group: * Exclusion Criteria: * Hypertension * Diabetes mellitus * Chronic kidney disease * Rheumatoid arthritis * Systemic lupus erythematosus * Cardiac illness * Severe neurological disorders * Immunological or systemic illness * Primary psychiatric disorders other than MDD and not in remission for MDD * Alcohol/drug/substance use 3. For Healthy Control (HC) Group: \*Inclusion Criteria: * No psychiatric diagnosis * No systemic or immunological illness * Medication-free for at least one month * Age ≥ 18 years * Provided informed consent For Healthy Control (HC) Group: \*Exclusion Criteria: * Hypertension * Diabetes mellitus * Chronic kidney disease * Rheumatoid arthritis * Systemic lupus erythematosus * Cardiac illness * Severe neurological disorders * Immunological or systemic illness * Having psychiatric disorders * Alcohol/drug/substance use 4. For Healthy Father and/or Mother of Bipolar Disorder Type II (BD-II) Group: \*Inclusion Criteria: * No psychiatric diagnosis * No systemic or immunological illness * Medication-free for at least one month * Age ≥ 18 years * Provided informed consent For Healthy Father and/or Mother of Bipolar Disorder Type II (BD-II) Group: \*Exclusion Criteria: • Hypertension * Diabetes mellitus * Chronic kidney disease * Rheumatoid arthritis * Systemic lupus erythematosus * Cardiac illness * Severe neurological disorders * Immunological or systemic illness * Having psychiatric disorders * Alcohol/drug/substance use 5. For Healthy Father and/or Mother of Major Depressive Disorder (MDD) Group: \*Inclusion Criteria: * No psychiatric diagnosis * No systemic or immunological illness * Medication-free for at least one month * Age ≥ 18 years * Provided informed consent For Healthy Father and/or Mother of Major Depressive Disorder (MDD) Group: \*Exclusion Criteria: • Hypertension • Diabetes mellitus • Chronic kidney disease • Rheumatoid arthritis • Systemic lupus erythematosus • Cardiac illness • Severe neurological disorders * Immunological or systemic illness * Having psychiatric disorders * Alcohol/drug/substance use 6. For Healthy Father and/or Mother of Healthy Control (HC) Group: \*Inclusion Criteria: • No psychiatric diagnosis • No systemic or immunological illness * Medication-free for at least one month * Age ≥ 18 years * Provided informed consent For Healthy Father and/or Mother of Healthy Control (HC) Group: \*Exclusion Criteria: * Hypertension * Diabetes mellitus * Chronic kidney disease * Rheumatoid arthritis * Systemic lupus erythematosus * Cardiac illness * Severe neurological disorders * Immunological or systemic illness * Having psychiatric disorders * Alcohol/drug/substance use
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Elazığ Fethi Sekin City Hospital
RECRUITINGElâzığ, 23200, Turkey (Türkiye)
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