Twin surgery study: which entry method is safer?
NCT ID NCT06829901
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at two common techniques surgeons use to enter the uterus during laser surgery for twin-to-twin transfusion syndrome. The goal is to see if one method causes less separation of the membrane around the baby. About 216 pregnant women with this condition will take part, and their outcomes will be compared.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If one entry technique clearly reduces membrane separation, it could become the preferred method, potentially improving outcomes for twin pregnancies.
- What could go wrong
- This is an observational comparison, not a test of a new treatment. It may not find a clear difference, and results may not apply to all patients or surgeons.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 216 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2025
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients who are eligible and elect to undergo fetoscopic selective laser photocoagulation for complicated monochorionic-diamniotic twin pregnancies with twin-to-twin transfusion syndrome. * Patients will be between 16 0/7 weeks and 26 0/7 weeks gestational age. Exclusion Criteria: * Patients who do not elect to undergo fetoscopic laser photocoagulation for the treatment of complicated monochorionic-diamniotic twin pregnancies with twin-to-twin transfusion syndrome. * Triplets and higher order multiple gestations. * Patients who are less than 16 0/7 weeks or greater than 26 0/7 weeks gestational age. * Patients with a short cervix (less than 1.5 cm). * Patients with a known subchorionic hemorrhage.
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Texas Children's Hospital - Pavilion for Women
RECRUITINGHouston, Texas, 77030, United States