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Can ancient massage and herbs soothe aching knees?

NCT ID NCT04492670

Symptom relief Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial investigates whether combining Tui-na, a traditional Chinese massage technique, with an oral herbal formula called Du-Huo-Ji-Sheng-Tang can reduce pain and improve function in people with knee osteoarthritis. Participants aged 50 and older with knee osteoarthritis will be randomly assigned to receive the combined therapy for four weeks or to a wait-list control group. The study measures changes in pain, stiffness, and quality of life using standard questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a combination of Tui-na (a type of Chinese therapeutic massage) and an oral Chinese herbal formula called Du-Huo-Ji-Sheng-Tang (DHJST)
What this could lead to
If effective, this combined therapy could offer a non-drug option for managing knee osteoarthritis symptoms like pain and stiffness.
What could go wrong
This is a small, early-stage trial with only 70 participants, so results may not apply widely. The treatment involves multiple components, making it hard to know which part works.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

70 people

The number who actually took part.

Started

Sep 2020

Finished

Oct 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. of either gender (female must have either sterilization done or menopause) 2. ≥50years of age 3. meet the criteria of KOA according to the American College of Rheumatology * Knee pain, and * Any 4 of the following, * ≥ 50 years of age * Less than 30 minutes of morning stiffness * Crepitus on active motion * Bony tenderness * Bony enlargement * No palpable warmth of synovium * Osteophytes (Radiographic findings) 4. with WOMAC score ≥ 39 5. with written informed consentform signed (for illiterate subjects, their next-of-kin or an impartial witness will sign with subjects' permission) Exclusion Criteria: 1. Known knee pain caused by infection, malignant or autoimmune diseases 2. Knee surgery or arthroscopy in the past year 3. Chondroprotective or intra-articular injection in the past 4 months 4. Systemic corticoid treatment in the past 4 months 5. Taking anticoagulants, antiplatelets, corticosteroids, psychiatric drugs, hormones, antiarrhythmic drugs or diuretics drugs 6. Subject with uncontrolled hypertension 7. Local antiphlogistic treatment, acupuncture, physiotherapy in the past 2 weeks 8. Known history of mental disorder 9. Known history of serious acute organic disease 10. Renal or liver function impairment 11. Known allergy to or have drug interaction with the study herb

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis

Contacts and locations

Locations

  • The Chinese University of Hong Kong

    Hong Kong, Hong Kong

More trials for these conditions

Other studies related to the condition(s) this trial covers.