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Spinal zap plus robot arm training shows promise for hand movement

NCT ID NCT07432321

Symptom relief Sponsor: National University Hospital, Singapore Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This small pilot study tests whether adding a gentle electrical stimulation to the spinal cord (tSCS) can make robotic arm training more effective for people with chronic tetraplegia from a spinal cord injury. Six to eight adults with neck-level injuries will first receive robotic training alone, then robotic training plus stimulation. Researchers will measure changes in arm strength, sensation, and quality of life. The goal is to see if the combination leads to better hand and arm function.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 6 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. At least 6 months to 5 years from the diagnosis of the traumatic SCI; 2. Participants between 21 and 80 years of age; 3. C2-8 level injuries; 4. ISNCSCI-UEMS \>25, 5. Pinch force \> 25 N; 6. Grasp force \> 100 N; 7. Able to perform the box and block test; 8. Sitting tolerance for at least 1 hour (No known postural hypotension issues or pressure intolerance); 9. Capable of providing an informed consent; 10. Cleared by Neurosurgeons/Orthopaedic Surgeon for tSCS; Exclusion Criteria: 1. Participant has uncontrolled cardiopulmonary disease or cardiac symptoms as determined by the investigator. 2. Participant has any unstable or significant medical condition that is likely to interfere with study procedures or likely to confound performance and outcomes like uncontrolled neuropathic pain, depression, severe cognitive impairment. 3. Unstable or uncontrolled autonomic dysreflexia. 4. Requires ventilator support. 5. Spasms that limit the ability of the subjects to participate in the study training as determined by the investigator. 6. Has an autoimmune etiology of spinal cord dysfunction/injury 7. History of additional neurologic disease, such as stroke, multiple sclerosis and traumatic brain Injury. 8. Pain in shoulder and/or hand which will be inhibitory towards rehabilitative therapy. 9. Severe Upper limb contractures. 10. Acute Medical conditions to Upper limb (ie Fractures that would limit ROM and/or weightbearing). 11. Participants who are pregnant.

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Conditions

The condition(s) this trial relates to.

spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Spinal cord injuries

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Alexandra Hospital

    RECRUITING

    Singapore, Singapore, 159964, Singapore

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