New hope for recurrent brain cancer: triple drug combo enters human trial
NCT ID NCT07263438
First seen Dec 16, 2025 · Last updated Apr 30, 2026 · Updated 21 times
Summary
This study tests whether combining an antidepressant (trimipramine) with two cancer drugs (atezolizumab and bevacizumab) can help people whose glioblastoma brain tumor has returned after standard treatment. About 59 participants will receive the drug combination for up to 2 years. The study has two groups: one to measure how well the treatment controls the tumor, and another to check how much trimipramine reaches the tumor tissue during surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
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Locations
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Bern Inselspital
RECRUITINGBern, Canton of Bern, 3010, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Centre Hospitalier Universitaire Vaudois
RECRUITINGLausanne, Canton of Vaud, 1011, Switzerland
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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HFR Fribourg - Hôpital cantonal
RECRUITINGFribourg, Canton of Fribourg, 1708, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Kantonsspital Aarau
RECRUITINGAarau, Canton of Aargau, 5001, Switzerland
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Luzerner Kantonsspital
RECRUITINGLucerne, Canton of Lucerne, 6000, Switzerland
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Contact Email: •••••@•••••
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Universitätsspital Basel
RECRUITINGBasel, Basel, 4031, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Universitätsspital Zürich
RECRUITINGZurich, Canton of Zurich, 8091, Switzerland
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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