Shorter PTSD therapy may be just as effective for veterans
NCT ID NCT05789329
First seen Jun 02, 2026 · Last updated Jun 20, 2026 · Updated 4 times
Summary
This study compares a shorter therapy focused on guilt (TrIGR) to a standard PTSD therapy (CPT) in 160 U.S. Veterans. The goal is to see if TrIGR is no less effective at reducing PTSD, depression, and guilt symptoms. Participants are randomly assigned to one of the two treatments.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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James A. Haley Veterans' Hospital, Tampa, FL
Tampa, Florida, 33612, United States
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VA San Diego Healthcare System, San Diego, CA
San Diego, California, 92161-0002, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Trauma Informed Guilt Reduction Therapy (TrIGR) and Cognitive Processing Therapy (CPT)
What this could lead to
If TrIGR works as well as CPT, it could offer a shorter, less resource-heavy option for treating PTSD in Veterans.
What could go wrong
This is a non-inferiority trial with 160 participants, so results may not apply to all Veterans. The therapy is behavioral, so individual responses vary.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.