Can antibiotics stop stunting? new trial targets gut bacteria in malnourished kids
NCT ID NCT07451171
First seen Mar 08, 2026 · Last updated Jun 19, 2026 · Updated 17 times
Summary
This study tests three different antibiotics to treat small intestine bacterial overgrowth (SIBO) in 60 malnourished Bangladeshi children. The goal is to find which antibiotic works best to clear the overgrowth, which may help prevent growth stunting and malnutrition. Children will receive one of the antibiotics for 15 days, and researchers will check if the bacteria are gone using a breath test.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b)
RECRUITINGDhaka, Bangladesh
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Trimethoprim-sulfamethoxazole, metronidazole, and amoxicillin-clavulanate (antibiotics)
What this could lead to
If successful, this trial could identify the best antibiotic to treat SIBO in malnourished children, potentially helping prevent growth stunting and malnutrition in low-income countries.
What could go wrong
This is a small, early-phase (IIa) study with only 60 children, so results may not apply broadly. The antibiotics may cause side effects or not effectively improve growth.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.