Immune cell test may predict kidney graft problems
NCT ID NCT04414111
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether measuring a specific type of immune cell (called highly suppressive Treg) before a kidney transplant can predict if the new kidney will work slowly or need dialysis. Researchers will test blood samples from 180 adult kidney transplant candidates. The goal is to find a reliable biomarker to guide organ allocation and reduce complications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors match donated kidneys to patients less likely to have complications, and guide new immune-based treatments.
- What could go wrong
- This is an observational biomarker study, not a treatment trial. The test may not accurately predict outcomes, and results may not change clinical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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180 people
The number who actually took part.
- Started
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Dec 2020
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Kidney transplant recipients
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- Adult kidney transplant candidates immediately prior to their kidney transplant surgery Exclusion Criteria: * \< 18 years old * Active immunosuppressive drug use * Hepatitis C * HIV
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Loma Linda University Health Transplantation Institute
San Bernardino, California, 92408, United States
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Saint Louis University
St Louis, Missouri, 63110, United States
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Other studies related to the condition(s) this trial covers.
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