Can a single drug dose forecast transplant kidney health?
NCT ID NCT03071536
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This trial investigates whether a standard dose of furosemide, a common diuretic, can serve as a stress test to predict how well a transplanted kidney will function. Participants receive the drug shortly after kidney transplant surgery, and their urine output is measured. The goal is to see if this response can help identify early signs of delayed graft function, potentially guiding post-operative care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Furosemide injection
- What this could lead to
- If successful, this could provide a simple, early test to predict how well a transplanted kidney will function, helping doctors tailor care sooner.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't change outcomes directly. The test's accuracy may vary, and it might not reliably predict long-term graft function.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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360 people
The number who actually took part.
- Started
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Nov 2016
- Finished
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Aug 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Deceased donor kidney transplantation at KCMH * informed consent is accepted Exclusion Criteria: * Known allergy to furosemide * Surgical complication of allograft * Urgently needed for dialysis (refractory hypervolemia, uremic symptoms, and hyperkalemia)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
King Chulalongkorn Memorial Hospital
Bangkok, Bangkok, 10330, Thailand
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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