Cheap arthritis drug could be new weapon against rare blood cancers

This study tests whether low-dose methotrexate (MTX), a safe and inexpensive drug used for decades in arthritis, can help people with certain blood cancers called myeloproliferative neoplasms (MPNs), including polycythemia vera, essential thrombocythemia, and myelofibrosis. Researchers want to see if adding MTX to current treatment can reduce spleen size, improve symptoms, and lower blood cell counts. The goal is to find an affordable option for patients who cannot access costly newer drugs.