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Butter vs. fake fats: which is worse for your health?

NCT ID NCT00617435

Knowledge-focused Sponsor: Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how different types of trans fats—one from dairy products and one from processed foods—affect insulin resistance in obese women. Sixty-six participants were given special diets to compare the effects. The goal was to understand if natural trans fats are less harmful than industrial ones.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
vaccenic acid enriched diet, elaidic acid enriched diet, control diet
What this could lead to
If successful, this could clarify whether natural trans fats from dairy are less harmful than industrial ones, guiding healthier dietary recommendations.
What could go wrong
This is a small, completed observational study with only 66 participants. Results may not apply to men or non-obese individuals, and dietary effects can vary widely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 66 people

The number the study aims to enrol. It can still change while the study runs.

Start date

Oct 2007

Finished

Jan 2009

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * female * waist measurement \> 88 cm * body mass index\> 28kg/m2 * Affiliated to National Health Insurance * Subject giving his/her written informed consent * Subject willing to comply with the study procedures * Subject considered as normal after clinical examination and medical questionnaire Exclusion Criteria: * Reported food allergies * Currently participating or having participated in another clinical trial during the last 4 weeks prior to the beginning of this study * Hepatic or renal impairments * Positive serologies to HIV or HCV, determined on blood sample * pregnant or presently attempting to get pregnant or menopause or lactating Blood donation done less than 2 months before the start of the study * Chronic pathologies: diabetes, hypertriglyceridemia, hypertension, cardiovascular diseases, chronic inflammatory diseases * Intestine, cardiovascular, kidney and cancer pathologies in the last 5 years * Previous heavy intestine surgery (except appendicectomy) * Previous medical and/or surgery judged by the investigator as incompatible with this study * High variation (\> 5%) of body weight during the last 3 months * Consuming nutritional supplements which could interfered with lipid metabolism (fish oil capsule, vitamins, soja lecithins,…) * Heavy consumer of alcohol * Smoker or ex-smoker who stopped smoking less than 1 month before V0 (more than 5 cigarettes/dy). * Practising intensive physical exercise (\> 5 h per week) * Vegetarian or vegan * Being under someone's supervision * Refusal to be registered on the National Volunteers Data file * Disliking butter, margarine, cheese, biscuits and/or vegetable oil * Dietary habits unreliable to controlled food intake * Being in exclusion on the National Volunteers Data file

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Conditions

The condition(s) this trial relates to.

Insulin Resistance Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Insulin resistance Obesity

Contacts and locations

Locations

  • Centre de Recherche en Nutrition Humaine Auvergne

    Clermont-Ferrand, 63000, France

  • Centre de Recherche en Nutrition Humaine Rhônes-Alpes

    Lyon, 69000, France

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