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Face-Off: which injection fades burn marks better?

NCT ID NCT07263841

Symptom relief Sponsor: King Edward Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two drugs—tranexamic acid and glutathione—given as tiny skin injections to lighten dark patches left by facial burns. Sixty adults with healed burns will receive both treatments on different halves of the same scar, and doctors will track improvement over six months. The goal is to see which works better and how safe they are.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
tranexamic acid and glutathione
What this could lead to
If this works, it could point toward a simple, non-surgical treatment to lighten dark patches on the face after burns.
What could go wrong
This is a small, early-phase trial with only 60 people. Results may not apply to everyone, and side effects like bruising or pain are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria:● Both sexes of WHO adult age group 18-65 years . * Patients with healed facial burns managed conservatively without skin grafting. * From 6 month to 12 month post burn injury (patient enrollment to be done before scar maturation starts) * Patients with Fitzpatrick skin types III to IV. * Patients with mental capacity to give informed consent. Exclusion Criteria:● Patients with documented hypersensitivity reactions to either drug or dressing etc. * History of de-pigmentation treatment, phototherapy. * Healed burn wounds with hypertrophic scar. * History of bleeding or clotting disorders, renal disease, collagen vascular disease and other photodermatoses3. * Pregnant or lactating females3. * Patients on hormone replacement therapy, oral contraceptives, concomitant use of anticoagulant, or any photosensitizing drug3.

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Conditions

The condition(s) this trial relates to.

Hyperpigmentation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post burn facial hyperpigmentation

Contacts and locations

Locations

  • King Edward Medical University

    Lahore, Punjab Province, 54000, Pakistan