New hope for kids with Hard-to-Treat brain tumors: targeted pill shows promise
NCT ID NCT03363217
First seen Apr 29, 2026 · Last updated Jun 17, 2026 · Updated 7 times
Summary
This study tests a daily pill called trametinib in children and young adults (ages 1 month to 25 years) with low-grade glioma or plexiform neurofibroma that has not responded to other treatments. The drug targets a specific pathway in the tumor cells. The goal is to see if the drug can shrink tumors and slow disease progression.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alberta Children's Hospital
Calgary, Alberta, T3B 6A8, Canada
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CHU Sainte-Justine
Montreal, Quebec, H3T 1C5, Canada
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CHU de Québec
Québec, Quebec, G1V 4G2, Canada
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Children and Women's Health Centre of British Colombia
Vancouver, British Columbia, Canada
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IWK Health Centre
Halifax, Nova Scotia, Canada
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Montreal Children's Hospital
Montreal, Quebec, H4A 3J1, Canada
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The Hospital for Sick Children
Toronto, Ontario, M5G 1X8, Canada
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.