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New hope for rare blood vessel disorder: targeted drug shows promise

NCT ID NCT04258046

First seen May 02, 2026 · Last updated Jun 17, 2026 · Updated 9 times

Summary

This study tested the drug trametinib in 25 people aged 12 to 60 with complicated arteriovenous malformations (AVMs), which are abnormal blood vessel tangles that can cause pain, bleeding, and heart problems. The goal was to see if the drug could shrink the malformations and improve symptoms. Participants took trametinib pills daily, and doctors monitored their response using scans and quality-of-life measures.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Pediatric Dermatology Clinic at Stanford Children's Hospital

    Palo Alto, California, 94304, United States

Conditions

The condition(s) this trial relates to.

arterial disorder arteriovenous hemangioma/malformation venous hemangioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.