New drug combo shows promise for Tough-to-Treat melanoma
NCT ID NCT03501368
First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 32 times
Summary
This early-phase study tested a combination of two drugs, trametinib and ceritinib, in 27 people with advanced melanoma that had stopped responding to standard treatments. The main goal was to find the safest dose and see if the combination could shrink tumors. While not a cure, the approach aims to control the disease in patients with few remaining options.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, 33612, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.