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Can running or yoga change how your body handles fat and sugar?

NCT ID NCT02150889

Knowledge-focused Sponsor: University of Minnesota Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how exercise training changes the way muscles process fat and sugar, which is linked to insulin resistance and type 2 diabetes. Researchers will study healthy, lean, and overweight participants before and after a 16-week running or yoga program. The goal is to understand how weight and training affect metabolism and insulin sensitivity.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could reveal how different exercise programs influence insulin resistance, potentially guiding future treatments for type 2 diabetes.
What could go wrong
This is an early-stage observational study with only 64 participants, so results may not apply to everyone. It measures metabolic markers, not actual disease outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

64 people

The number who actually took part.

Started

Jul 2014

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: All subjects 1. Subjects 18 to 40 years of age. 2. Subjects are capable of giving informed consent Overweight or obese 1. Insulin resistant based on screening oral glucose tolerance testing. 2. BMI 25 to 40 kg/m2 inclusive 3. Stable weight for at least 3 months (± 5 lbs.) 4. Sedentary status (self-report \< 30 minutes/week regular exercise). Lean, physically active 1. physically active subjects defined as 3-5 aerobic exercise sessions/week 2. matched to age and gender 3. generally healthy with normal fasting glucose levels (glucose ≤100 mg/dL). Exclusion Criteria: All subjects 1. Subjects 18 to 40 years of age. 2. Subjects are capable of giving informed consent Overweight or obese 1. Insulin resistant based on screening oral glucose tolerance testing. 2. BMI 25 to 40 kg/m2 inclusive 3. Stable weight for at least 3 months (± 5 lbs.) 4. Sedentary status (self-report \< 30 minutes/week regular exercise). Lean, physically active 1. physically active subjects defined as 3-5 aerobic exercise sessions/week 2. matched to age and gender 3. generally healthy with normal fasting glucose levels (glucose ≤100 mg/dL).

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Insulin Resistance Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy subjects Lean trained subjects Overweight and obesity

Contacts and locations

Locations

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.