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Why does topiramate work for some teens but not others? scientists investigate.

NCT ID NCT04986631

First seen Dec 10, 2025 · Last updated May 20, 2026 · Updated 18 times

Summary

This study looked at why the weight-loss drug topiramate works differently in different teenagers with severe obesity. Researchers used mathematical models to understand how the drug moves through the body and affects weight. The goal was to find ways to personalize dosing for better results. 62 teens aged 12 to 18 took part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.