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New topical treatment shows promise for rare tongue condition

NCT ID NCT04128722

First seen Jan 04, 2026 · Last updated Jun 14, 2026 · Updated 21 times

Summary

This study tested a daily dab of sirolimus solution on the tongue for people with a rare condition causing fluid-filled cysts on the tongue. The goal was to see if it could reduce symptoms like oozing, bleeding, and trouble eating or speaking. Twelve children and adults used the treatment for up to 24 weeks, and doctors checked for improvement using photos and patient reports.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital NECKER -AP-HP - Dermatology

    Paris, 75015, France

  • Univsersity of TOURS _ Service de Dermatologie

    Tours, Indre et Loire, 37044, France

Conditions

The condition(s) this trial relates to.

microcystic lymphatic malformation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.