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New study tracks gout crystal shrinkage with advanced CT scans

NCT ID NCT03965676

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 21 times

Summary

This study follows 50 adults with tophaceous gout to see how urate-lowering therapy reduces crystal deposits in hands and feet over 6 months. Using a special CT scan, researchers measure changes in crystal volume and check if bone erosions heal. The goal is to understand why some tophi shrink faster than others and how this affects joint health.

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Contacts and locations

Locations

  • Radiology Department Lariboisière Hospital

    Paris, Île-de-France Region, 75010, France

  • Reumatology Department Lariboisière Hospital

    Paris, Île-de-France Region, 75010, France

Conditions

Explore the condition pages connected to this study.