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Which onlay lasts longest? new study pits three materials Head-to-Head

NCT ID NCT07157410

Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares three different tooth-colored onlay materials used to repair back teeth with deep cavities that extend below the gum line. Each of the 18 adult participants will receive three onlays made from different materials. Researchers will check the onlays at 2 weeks, 6 months, 18 months, and 24 months to see how well they hold up, whether they cause sensitivity, and if new decay develops. The goal is to identify which material performs best for this type of dental restoration.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dental onlay materials (lithium-disilicate ceramic and composite resin)
What this could lead to
If successful, this could help dentists choose the most durable and safe onlay material for repairing deep cavities in back teeth.
What could go wrong
This is a small, early-stage study with only 18 participants, so results may not apply to everyone. Some onlays may chip, loosen, or cause sensitivity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 18 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Molar tooth with proximal subgingival carious lesion of ICDAS 4 or 5, causing weakening of one or more cusps. 2. Normal alignment with the adjacent and opposing teeth. 3. Acceptance of the follow-up period and recall visits for 2 years. Exclusion Criteria: 1. Distance between the gingival margin and the crestal bone \< 2 mm. 2. The tooth would require direct pulp capping. 3. Poor oral hygiene (or not completing the oral hygiene phase). 4. Chronic periodontitis. 5. Pulpitis or non-vital tooth. 6. Orthodontic treatment. 7. Parafunctional habits. 8. Systemic disease. 9. Pregnancy. 10. Teeth act as abutment for fixed or removable prosthesis. 11. Occlusion of fewer than 20 teeth

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Clinical performance of cervical-margin-relocated onlay restorations Indirect tooth-colored onlay restorations in posterior teeth

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Dentistry, Mansoura University

    RECRUITING

    Al Mansurah, Dakahlia Governorate, 35516, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.