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Whitening without the ouch? study tests best way to brighten smiles

NCT ID NCT07173296

Symptom relief Sponsor: King Abdullah University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at whether using a tooth-whitening gel in one long session or several short sessions changes how much tooth pain people feel and how white their teeth get. About 60 adults with darker teeth will receive one of two common whitening gels. Researchers will measure pain using simple scales and check color changes with a shade guide and a special device.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
tooth bleaching gel (hydrogen peroxide 37.5% or 40%)
What this could lead to
If successful, this could help dentists choose a whitening method that causes less tooth pain while still working well.
What could go wrong
This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. Tooth sensitivity is still possible with any bleaching method.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * At least eight maxillary anterior teeth present. * Age over 18 * The selected teeth have a mean shade of C2 or darker. * Good general and oral health. (no visible plaque or gingivitis) * No restorations or carious lesions on the buccal surfaces of the anterior teeth to be whitened * No history of tooth sensitivity * No use of a desensitizing agent or desensitizing toothpaste in the past six months * No use of pain killer for the last 48 hours Exclusion Criteria: * Active caries and/or periodontal diseases (gingivitis and recession) or wasting diseases * Smokers * Pregnant/lactating women. * Patients who have bleached their teeth previously. * No schedule availability

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Conditions

The condition(s) this trial relates to.

allergic disease dentin sensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tooth sensitivity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Jordan University of Science and Technology

    RECRUITING

    Irbid, Jordan

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