Can extra phone support help smokers quit during lung screening?
NCT ID NCT06290869
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two smoking cessation programs for people undergoing lung cancer screening. About 1,188 participants will either receive phone counseling and nicotine replacement from a health system or be referred to a quitline. The goal is to see which approach leads to more people quitting smoking and staying smoke-free.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- phone-based tobacco treatment and nicotine replacement therapy (patches and lozenges)
- What this could lead to
- If successful, this could show a more effective way to help smokers quit during lung cancer screening, reducing their cancer risk.
- What could go wrong
- This is a large trial, but quitting smoking is very hard, and the extra support may not lead to lasting abstinence. Results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 1,188 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2024
- Expected to finish
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Mar 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * eligible for a screening or diagnostic scan, * USPSTF eligibility criteria (50-80 years old and \>20-pack years); * currently smoking cigarettes (\>1 in the past 30 days); * English speaking; * able to provide meaningful consent. Exclusion Criteria: * prior lung cancer, * hearing impairment, * cognitive impairment, * household member already enrolled.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Georgetown University Medical Center
RECRUITINGWashington D.C., District of Columbia, 20007, United States
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