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New TMS therapy aims to quiet tics in kids without drugs

NCT ID NCT07351955

Symptom relief Sponsor: Shanghai Children's Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a personalized, non-invasive brain stimulation technique (TMS) in 60 children aged 5-18 with tic disorders. The goal is to reduce tic severity and understand how the brain changes with treatment. Children also receive behavioral guidance, such as avoiding triggers. The trial is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Transcranial magnetic stimulation (TMS) device
What this could lead to
If it works, this could offer a non-invasive, personalized treatment to reduce tics in children, potentially improving daily life without medication.
What could go wrong
This is an early study with only 60 participants, so results may not apply to all children. TMS may cause discomfort or not reduce tics significantly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

5 months to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1: Children and adolescents aged 5 to 18 years 2: Meets DSM-5 diagnostic criteria for Tic Disorders (TDs) with normal EEG findings 3: No prior treatment received for TDs 4: Full-scale intelligence quotient (FIQ) ≥70 on the Wechsler Intelligence Scale for Children-Revised (WISC-R) Exclusion Criteria: * 1: WISC-R Full-Scale Intelligence Quotient (FIQ) \<70 2: Presence of metal implants in the body ，Non-right-handedness 3: Head movement (HM) \>2mm during fMRI scanning, including both translational movement (TM) and rotational movement (RM) 4: Any other neurological or psychiatric conditions, including but not limited to autism spectrum disorder (ASD), epilepsy, obsessive-compulsive disorder (OCD), etc 5: Previous head trauma ，Neurological diseases ，Major systemic illnesses

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Conditions

The condition(s) this trial relates to.

tic disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tic disorders

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Shanghai Children's Medical Center，School of Medicine, Shanghai Jiao Tong University

    RECRUITING

    Shanghai, Shanghai Municipality, 200127, China

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