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Brain zaps may tweak hormones: early study tests TMS on healthy women

NCT ID NCT07363421

Knowledge-focused Sponsor: The City College of New York Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This small study tests whether transcranial magnetic stimulation (TMS), a non-invasive brain stimulation technique, can alter levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in healthy women. Ten women in the luteal phase of their menstrual cycle will receive both active and sham TMS to see if hormone levels change. It is a feasibility study, meaning it aims to see if the approach works at all, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Transcranial Magnetic Stimulation (TMS)
What this could lead to
If it works, this could point toward a non-invasive way to influence hormones, potentially helping with hormone-related conditions.
What could go wrong
This is a very small, early feasibility study in healthy women, not a treatment trial. It may not show any effect or translate to clinical use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 10 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

22 to 40 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy women aged 22-40 years with regular menstrual cycle. * In luteal phase at the time of visit. Exclusion Criteria: * Presence of any known structural brain abnormalities or tumors. * Presence of metal implants/devices in the head or neck. * Has ever had a stroke, seizure, or has a family history of epilepsy. * Head injury with loss of consciousness. * Use of hormonal contraceptives in the past 3 months. * Irregular menstrual cycles. * Diagnosed with a reproductive system disorder (e.g., PCOS, endometriosis, infertility, hypogonadism). * History of endocrine disorders such diabetes mellitus, thyroid disease, adrenal disorders, pituitary tumor or others. * Been diagnosed or received treatment for depression, anxiety disorder, schizophrenia, PTSD or bipolar disorder. * Have a history of medical disorder such liver or renal impairment, HIV/AIDS or unstable cardiac disease. * Taking any medications that affect the central nervous system such as antidepressents, antipsychotics, GLP-1 receptor agonists or hormone therapies. * Are you pregnant, planning pregnancy or breastfeeding. * Have experienced difficulties in the past during blood draws such as locating the vein, fainting or other adverse reactions. * Have any sleep disorder such as insomnia or sleep apnea. * Have fear of needles or the sight of blood. * Underwent TMS stimulation in the past and had difficulties.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy women

Contacts and locations

Locations

  • Site 1

    New York, New York, 10010, United States

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