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Own blood injections may ease jaw arthritis pain
NCT ID NCT06839326
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two treatments for jaw joint arthritis (TMJ osteoarthritis): platelet-rich plasma (PRP) and autologous conditioned serum (ACS), both made from the patient's own blood. 75 adults who had not improved with standard care received one of these injections after a joint washout procedure. The goal was to see which treatment better reduces pain and improves mouth opening.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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75 people
The number who actually took part.
- Started
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Nov 2024
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Over 18 years old * Previously received conservative treatment but no improvement in symptoms * Patients with TMJ osteoarthritis Exclusion Criteria: * Patients who have experienced TMJ trauma or have undergone surgical procedures in this region will be excluded from the study. * Patients with facial growth disorders, systemic inflammatory joint diseases, condylar pathologies, or signs of myalgia * Patients who are pregnant or in the lactation period
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Batman University
Batman, Centre/Batman, 72100, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.