New hope for rare brain cancer: tirabrutinib trial targets relapsed lymphoma
NCT ID NCT07104032
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 24 times
Summary
This study tests if the drug tirabrutinib works better than a combination of two standard drugs (rituximab and temozolomide) for people with a rare type of brain lymphoma that has returned or not responded to prior therapy. About 132 adults with this condition will be randomly assigned to receive either tirabrutinib alone or the standard combination. The main goal is to see how long the cancer stays under control.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02115, United States
Contact
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02115, United States
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HonorHealth Cancer Center
RECRUITINGScottsdale, Arizona, 85251, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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Providence Medical Foundation
RECRUITINGFullerton, California, 92835, United States
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UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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Yale Cancer Center
RECRUITINGNew Haven, Connecticut, 06520, United States
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Conditions
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