Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Feeding delay after esophageal surgery studied for muscle preservation

NCT ID NCT03676478

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to see if delaying feeding for a few days after esophageal cancer surgery helps protect muscle mass and improve recovery. It included 239 adults with esophageal cancer who were scheduled for surgery. The study was stopped early, so results are limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

239 people

The number who actually took part.

Started

Mar 2019

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Candidates for surgical resection with a curative intent, admitted to our Department. * Able to understand the study information in Dutch or French and tasks related to the study measurements provided by the researchers. * Able to consent. * Patients with cancer of the gastroesophageal junction (GEJ), distal, mid- and proximal thoracic esophagus. * Patients with early as well as advanced clinical stage esophageal cancer: from clinical stages cT1N0 over cT2+ N+ or cT3 Nx after neo-adjuvant therapy or at the time of staging as a candidate for primary surgery. * Histology preop: Squamous or adenocarcinoma. * Patients must undergo at least two-field lymphadenectomy; three-field lymphadenectomy if deemed necessary by the clinical team is not a contraindication for inclusion. * All access: (robotic assisted) minimal invasive (thoracoscopy \& laparoscopy) approach, left thoraco-abdominal incision, hybrid esophageal resection or R thoracotomy + laparotomy * Partial or subtotal esophagectomy. * Reconstruction by gastric conduit. * All anastomoses (intrathoracic or cervical). * Women of child bearing age with esophageal cancer can be included. Exclusion Criteria: * Patients in a definitive chemoradiation protocol, or undergoing rescue resection following definitive chemoradiotherapy. * Patients expected to die within 12 hours (=moribund patients). * Patients transferred from another institute after esophageal resection with an established nutritional therapy. * Patients with a cT4b tumor after neo-adjuvant therapy. * Patients who are at the time of surgery deemed unresectable or found to be unresectable during surgery. * Patients with a R2-resection. * Patients with metastasis at the time of clinical staging. * Patients undergoing transhiatal resection of the esophagus. * Patients undergoing total gastrectomy * Patients undergoing an esophageal resection or esophageal bypass as palliative treatment * Patients with tumors in the cervical esophagus with a distance less than 3cm from the cricopharyngeal sphincter. * Patients with pharyngeal cancer undergoing (laryngo-)pharyngectomy with gastric pull-up * Need for colonic or jejunal interposition * Patients with a second synchronous malignancy * Patients with inflammatory bowel disease (as this might interfere with caloric uptake in the small bowel) * Patients with contra-indications for enteral nutrition. * Patients already participating in a study with a nutritional intervention.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Esophageal cancer are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms Muscle Weakness Postoperative Complications Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospitals Leuven, dept. of Thoracic Surgery

    Leuven, 3000, Belgium

More trials for these conditions

Other studies related to the condition(s) this trial covers.