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Afternoon workouts may beat morning sessions for blood sugar control

NCT ID NCT06014684

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether exercising in the afternoon versus the morning makes a difference in blood sugar levels for people with pre-diabetes. Fifteen overweight adults aged 40-75 completed a 12-week high-intensity interval training program. The main goal was to see if afternoon exercise improves overnight glucose levels and insulin sensitivity more than morning exercise.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High Intensity Interval Training (HIIT) exercise program
What this could lead to
If successful, this could show that timing exercise in the afternoon is a simple way to better manage blood sugar in people with pre-diabetes.
What could go wrong
This is a very small, completed study with only 15 participants. Results may not apply to everyone, and the effect of exercise timing may be minimal or not reproducible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

15 people

The number who actually took part.

Started

Jul 2023

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 40-75 years. * Body mass index (BMI) ≥25 kg/m2 * Male, or postmenopausal (at least 1 year post cessation of menses) female * Pre-diabetes based on one or a combination of the following criteria: * Impaired Glucose Tolerance (IGT): plasma glucose values ≥ 7.8 mmol/l and ≤ 11.1 mmol/l 120 minutes after glucose drink consumption during OGTT in screening * ImpairedFastingGlucose(IFG):Fastingplasmaglucose≥6.1mmol/land≤6.9 mmol/l * Insulin Resistance: glucose clearance rate ≤ 360 mL/kg/min, as determined during the OGTT using OGIS120. * HbA1cof5.7-6.4% Exclusion Criteria: * Type 2 diabetes * Patients with active congestive heart failure and and/or severe renal and or liver insufficiency * Uncontrolled hypertension * Any contra-indication for MRI scanning * Alcohol consumption of \>3 servings per day for man and \>2 servings per day for woman * Smoking * Unstable body weight (weight gain or loss \> 5kg in the last 3 months) * Previous enrolment in a clinical study with an investigational product during the last 3 months or as judged by the Investigator which would possibly hamper our study results. * Medication use known to hamper subject's safety during the study procedures. * Subjects who do not want to be informed about unexpected medical findings. * Men: Hb \<8.0 mmol/L, Women: Hb \<7.0 mmol/l * Heavily varying sleep-wake rhythm (i.e. night shift work and travels across time zones). * Significant food allergies/intolerance (seriously hampering study meals) * Blood donation during or within 2 months prior to the study

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Maastricht University

    Maastricht, Limburg, 6229 ER, Netherlands

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