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Feeding clock ticked: Time-Restricted nutrition may boost stroke outcomes

NCT ID NCT06161948

Disease control Sponsor: First Affiliated Hospital of Wannan Medical College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving tube-feeding only during an 8-12 hour window each day (instead of continuously) improves recovery in 420 severe stroke patients. Participants had either a brain bleed or clot and were followed for 90 days to see if they had less disability. The approach is simple and could be easily adopted if proven effective.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
time-restricted enteral nutrition (feeding schedule)
What this could lead to
If it works, this could point toward a simple feeding schedule that improves recovery after severe stroke.
What could go wrong
This is a completed trial, but results are not yet widely confirmed. The approach only applies to patients needing tube feeding, and individual responses may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

420 people

The number who actually took part.

Started

Jan 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years old and \<80 years old; * Cerebral parenchymal hemorrhage or cerebral infarction within 72 hours of onset; * GCS score ≤12 points or NIHSS score ≥11 points on admission, * Enteral nutrition is planned, and the estimated enteral nutrition treatment time is ≥7 days; * Signed informed consent form. Exclusion Criteria: * Complete parenteral nutrition is required due to contraindications to enteral nutrition; * After gastrectomy or intestinal resection; * Enteral nutrition treatment has been performed for \>12 hours; * Accompanying diseases: a. Advanced cancer; b. Severe cardiac insufficiency \[ejection fraction ≤ 50%\]; c. Severe liver failure \[Child Pugh score ≥ 7\]; d. Severe renal failure \[glomerular filtration\] rate ≤ 30 mL/min or serum creatinine ≥ 4 mg/dL\]) * Have a history of mental illness or mRS ≥ 3 points; * The patient's doctor or nutritional therapist believes that the plan is not in the best interest of the patient; * During the patient's admission, death is inevitable, and there are underlying diseases that result in a survival time of \<90 days; * The patient participates in another clinical study.

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Conditions

The condition(s) this trial relates to.

Intermittent Fasting stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke Time restricted feeding

Contacts and locations

Locations

  • The first affliated hospital of Wannan medical college

    Wuhu, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.