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Can fasting plus a diabetes drug shrink breast tumors?

NCT ID NCT05023967

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 23 times

Summary

This study looks at whether combining a nightly fasting period with the diabetes drug metformin can slow the growth of early-stage breast cancer. About 120 women with hormone-sensitive breast cancer or a pre-cancer condition called DCIS will follow a fasting schedule and take metformin before their surgery. The goal is to see if this approach reduces tumor cell growth and other cancer-related markers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • European Institute of Oncology

    Milan, 20141, Italy

  • Galliera Hospital

    Genoa, 16128, Italy

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.